Upperton joined by Oxford/AstraZeneca COVID-19 vaccine co-inventor to open new development and GMP manufacturing facility

Contract development and manufacturing organisation (CDMO) Upperton Pharma Solutions was joined by Oxford/AstraZeneca COVID-19 vaccine co-inventor Professor Dame Sarah Gilbert, biotech industry representatives and local leaders to celebrate the official opening of a new 50,000 square foot development and GMP manufacturing facility in Nottingham. In addition to Professor Dame Sarah Gilbert, the plaque-unveiling ceremony included local Member of Parliament, Darren Henry MP, and leading industry professionals. Nikki Whitfield, CEO of Upperton Pharma Solutions, said: “This celebration marks another milestone in our incredible growth journey as a business. We are looking forward to officially opening our doors to customers and offering a single site solution for development and GMP manufacturing.” “It was a pleasure to join Upperton for the grand opening of their new facility,” said Guest of Honour, Professor Dame Sarah Gilbert, Principal Investigator at the Pandemic Sciences Institute, University of Oxford and co-creator of the Oxford/AstraZeneca COVID-19 vaccine. “During the pandemic we saw the importance of academia and industry working closely together to deliver life-saving vaccines and treatments. Upperton’s expansion into this new site is a great example of the crucial role UK-based pharmaceutical organisations have to play in addressing global health challenges. I look forward to collaborating with Upperton in the future.” The new facility contains ten GMP manufacturing suites, cutting-edge quality control laboratories, and formulation development capabilities equipped with a pilot plant. The facility empowers Upperton to offer customers a seamless transition from early formulation development to clinical trial supplies from Phase 1 to Phase 3 and niche scale commercial manufacturing all on one site. The official opening marks another milestone for Upperton following the announcement and ongoing build of a new sterile facility on the same site, for the manufacturing of aseptic and terminally sterilized small volume liquids for parenteral, ocular and pulmonary delivery due for completion at the end of 2024.

Manufacturing output falls but firms expect modest rise in quarter ahead

Manufacturers reported that output volumes fell in the three months to March, and at a similar pace to the three months to February, according to the CBI’s latest Industrial Trends Survey (ITS). However, manufacturers expect output to rise modestly in the quarter to June. Expectations for future selling price inflation edged up for the third successive month in March, with the balance rising further above its long-run average to its highest since May 2023. Total order books were steady compared with last month, and a little below their long-run average, but export order books deteriorated. The survey, based on the responses of 289 manufacturers, found:
  • Output volumes fell in the three months to March, at a similar pace to the quarter to February (weighted balance of -18%, from -19% in the three months to February), and disappointing expectations for marginal growth (+4%). Output is expected to rise modestly in the three months to June (+8%).
    • Output fell in 11 out of 17 sub-sectors in the three months to March, including the chemicals, motor vehicles & transport equipment, plastic products and metal products sub-sectors.
  • Total order books were reported as below “normal” in March and were broadly unchanged relative to last month (-18% from -20%) at a level slightly below the long-run average (-13%).
  • Export order books were also seen as below normal and deteriorated relative to last month (-29% from -14%) to below the long-run average (-18%).
  • Expectations for average selling price inflation accelerated in March (+21%, from +17% in February)—comfortably above the long-run average (+7%) and to the greatest extent since May 2023.
  • Stocks of finished goods were seen as more than “adequate” in March (+12% from +11% in February), with stock adequacy broadly unchanged since the previous month (+12% from +11% in February), in line with the long-run average.
Anna Leach, CBI Deputy Chief Economist, said: “It’s disappointing that manufacturing output volumes fell in the first three months of the year, underperforming last month’s expectations for a slight upturn. But manufacturers remain optimistic that conditions will improve in the quarter ahead. “Manufacturers expect selling prices to rise a little in the months ahead. With demand still subdued, this likely reflects some pressure on input costs over recent months, slightly higher oil prices, higher shipping costs amid the Red Sea disruption, and signs that the global industrial cycle is beginning to turn upwards after a difficult couple of years. “In a general election year, all parties must focus on fostering a business environment that will give UK manufacturers the confidence they need to invest and compete globally. The Chancellor’s announcement of plans to extend full capital expensing to leased and rented assets was a welcome step that will help smaller and medium-sized manufacturers in particular, but more clarity over its implementation would be welcomed.”

Summer start for major work to regenerate Chesterfield town centre

The next phase of a multi-million pound project to regenerate Chesterfield town centre is set to get underway this summer.

Chesterfield Borough Council’s ‘Revitalising the Heart of Chesterfield’ project – which has already seen good progress on work to refurbish the iconic Stephenson Memorial Hall, as well as improvements to Packers Row – will transform the look, feel and flow of key public spaces.

The detailed timescales are being finalised, but it is expected that work to revamp the town’s historic market place, which includes New Square and Market Square, will start in summer.

Key improvements will include:

  • Market Square – the historic market will be revitalised – with a new layout to make it easier to walk around, new stalls with modern facilities for traders, and vibrant new canopies in heritage colours. The plans will also ensure the historic Town Pump is made into a unique feature in this space.
  • New Square – the plans will create an attractive and flexible space that will complement the main market and speciality markets, but can also be used to host festivals, events, cultural celebrations, and community gatherings – bringing the town centre to life.
  • Rykneld Square – this area will be transformed to create a more welcoming, green space from which to enjoy the much-loved Crooked Spire, and better connect this landmark to the town centre.
  • Spire Walk – the council will work in partnership with the Church of St Mary and All Saints to create a more welcoming and attractive space in which to enjoy the iconic Crooked Spire, this includes imaginative new lighting that will enhance the appearance of the spire at night and link into Rykneld Square.
  • Corporation Street – improved paving and lighting will revamp this key gateway to the town centre and provide a welcoming environment for visitors to the refurbished theatre and museum. This will provide an attractive and welcoming new gateway to the refurbished Stephenson Memorial Hall.

Attractive lighting, new digital facilities, more greenery, new seating and signage will feature across the regeneration sites – creating a more attractive, welcoming and safe town centre for everyone to enjoy.

Councillor Kate Sarvent, cabinet member for town centres and visitor economy, said: “We’re immensely proud of our town and these widespread improvements will create a revitalised and vibrant town centre that builds on our strong history and heritage, supporting it to thrive for generations to come.

“A lot of work has been happening behind the scenes to get to this stage, including ongoing conversations with our market traders, businesses and residents, and we’re excited to look ahead to a start on site in the summer.

“Chesterfield certainly has positive times ahead, with the major refurbishment work at Stephenson Memorial Hall – home to our beloved theatre and museum – also progressing well.”

The Revitalising the Heart of Chesterfield project will be completed in phases and is due for completion in 2025.

Councillor Sarvent added: “We have a strong track record of making the most of external funding opportunities to invest in the future of our borough, and through projects like the Revitalising the Heart of project this work will bring real improvements for the residents and businesses of our town, while boosting our appeal to visitors.”

The project will complement improvements at the Northern Gateway and Elder Way and – at the other side of town – will connect with plans to transform the area around Chesterfield Station.

Planning submitted for landmark building forming key part of Staveley town centre regeneration

Plans for a new landmark building which would form a key part of the Staveley town centre regeneration project have been formerly submitted.

The new landmark building if approved will form a key part of the £6 million Staveley 21 project which will transform the market place, enhance the connections to the Chesterfield Canal and improve lighting in the town centre.

Funding for the project has been provided through the Staveley Town Deal.

Councillor Kate Sarvent, Chesterfield Borough Council’s cabinet member for town centres and visitor economy, said: “This project aims to transform Staveley town centre – enhancing the area and encouraging more people to visit and support both existing retailers and market traders. Town centres are changing and by trying to expand the offer, creating new opportunities for events and social spaces we want to boost visitor numbers and provide the space for local businesses to thrive.

“We’ll continue to engage directly with local businesses and residents over the coming months to finalise the plans and ensure the project meets their needs, including hosting more drop-in sessions for residents.”

If approved the new landmark pavilion building will sit between the Staveley Miners Welfare building and Staveley High Street as a striking new focal point in the heart of the town centre.

The building aims to reflect Staveley’s heritage with a modern twist, opening the view from Market Street into the town centre. Several uses for the building are currently being considered including as a potential site for Staveley library and is also being considered for retail, leisure, and business start-up uses.

In November regional construction contractor Stepnell were appointed to finalise the plans for the town centre and begin working towards delivery.

Tom Sewell, regional director at Stepnell, said: “We bring vast experience of collaborating with local authorities and partners to enhance public town centre spaces, and, as a complete construction partner, we aim to deliver exceptional quality throughout the design and build.

“By being sympathetic to the needs of residents and businesses in the town, Staveley 21 will enhance the wider package of works as part of the Staveley Town Deal. We look forward to working with Chesterfield Borough Council to deliver the Staveley 21 project, which will generate lasting value to the community.”

The building has been designed by Whittam Cox Architects, who are based in Chesterfield.

Ryan Fish, associate director at Whittam Cox Architects, said: “Our team have meticulously developed the Pavilion building as part of the Staveley centre masterplan with utmost care and consideration. This project presented us with a unique opportunity to influence a scheme close to home, drawing on our intricate knowledge of the local area.

“The result is a contemporary development that not only honours Staveley’s heritage but also serves as a catalyst and hub of activity for future development, aligning with the long-term vision for the area.”

Staveley 21 also includes the transformation of the market place to create an enlarged public space to support existing uses such as Staveley Town Council’s regular markets but also as a setting that can be used to host a wide range of new events to encourage more people to visit the town centre.

Proposals include new tiered outdoor seating to support outdoor theatre and open-air cinema screenings, and natural play equipment to help make the marketplace more attractive to families.

New paving, lighting, street furniture and planting will help create an enhanced atmosphere and visitor experience at any time of day or night whilst new signage will help connect the town centre with Staveley’s other visitor attractions including the Chesterfield Canal and Staveley Hall.

There is also a shop front improvement grant scheme for businesses based in the town centre. Up to 80% of the costs of shop front improvements like new signage, windows, canopies, and much more can be funded through the scheme.

Ivan Fomin, chair of the Staveley Town Deal Board, said: “The Staveley 21 project has the potential to be transformative for the town centre, ensuring that it is a place where local people and visitors will want to spend time whilst also supporting local businesses to grow not only now but in the future.

“Our aim through the town deal is ensuring that Staveley is a place where people can Start, Stay and Grow and the town centre reflects this with something to entice all ages to visit, support local businesses and to help them to grow.”

Streets Chartered Accountants covers Virtual Finance Offices, Working Capital Cycles, Annual Tax on Enveloped Dwellings, and more in new news roundup

Streets Chartered Accountants covers Virtual Finance Offices, Working Capital Cycles, Annual Tax on Enveloped Dwellings, and more in its latest monthly news roundup.

New Virtual Finance Office (VFO) service

We are often asked what is a Virtual Finance Office or VFO? A Virtual Finance Office replaces the more traditional in-house finance department or team, with an external third-party virtual finance team.

Outsourcing your finance function often involves the sending out of work just for processing. In contrast a Virtual Finance Office not only provides the processing of transactions and production of information, but also greater additional financial input, support and advice. Read more.

Every business has a working capital cycle. This is the time it takes for your business to turn net current assets into available cash.

The longer the working capital cycle, the more time it takes for your business to get a robust cash flow. It’s good practice for businesses to manage their cycle by looking at each step where possible. This could be by selling stock or product quicker, collecting monies owed sooner and possibly paying bills later on. Read more.

However, the charge can apply to any UK residential property wholly or partly owned by a company (including a partnership with a corporate member). Read more.

The Budget 2024 – catch up!Last week Streets hosted a post Budget webinar, ​​​​​​​providing details of the announcements along with an update on topical issues affecting business clients and private individuals for the new tax year 2024/25.

This presentation was recorded and is now available on demand for those who weren’t able to join live. Watch now.

Chesterfield packaging manufacturer sees mixed year

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Robinson plc, the custom manufacturer of plastic and paperboard packaging, ended 2023 “with a much stronger business,” its Chairman has said in audited results for the year to 31 December 2023.

While operating profit before exceptional items and amortisation of intangible assets increased to £2.2m, from £2m in 2022, revenue was down 2% to £49.7m, from £50.5m in 2022. Meanwhile, the company posted a loss before tax of £0.7m, in comparison to a £2.3m profit in the year prior.

Alan Raleigh, Chairman, said: “Robinson ended 2023 with a much stronger business. We improved adjusted operating profits, achieved surplus property sales, and secured the return of the pension escrow account funds to reduce gearing and strengthen our balance sheet.

“We have largely renewed our manufacturing asset base, won important new business with leading FMCG customers and are now seeing sales volumes recover.

“We have taken the necessary actions to make Robinson more resilient, more competitive, and more responsive. As market conditions begin to improve, we are well placed to generate sustainable long-term value for our shareholders. 

“Following improved momentum in the second half of 2023, and reflecting the effect of new customer projects and the full year impact of cost savings, the Company expects revenue, and operating profit (before amortisation of intangible assets and any exceptional items), for the 2024 financial year to be ahead of 2023. We remain committed in the medium-term to delivering above-market profitable growth and our target of 6-8% adjusted operating margin.”

336-acre sustainable urban extension scheme in Skegness gains approval

Plans to transform part of the East Lincolnshire coast have taken an important step forward, following unilateral approval of the 336-acre sustainable urban extension scheme in Skegness. The news, delivered Wednesday 20 March at an executive meeting of East Lindsey District Council in Horncastle, means the town is on the cusp of receiving more than £300 million in economic benefits, delivering hundreds of local jobs. Projections undertaken by the Gateway team showcase the scheme will deliver employment benefits of £289.7 million, £20.5 million and £16 million in Gross Value Added (GVA) measurability for commercial, industrial and retail sector jobs. The proposed Local Development Order is seeking to expedite the delivery of up to 1,000 new homes and more than 49 acres of combined business, industrial and community space. Situated to the west of the town, on land principally owned by Croftmarsh, with additional areas owned by the Scarbrough family, the Skegness Gateway scheme is set to breathe new life into an area of the Lincolnshire coast that drastically needs change in order to secure its future, boosting the local economy and providing the education and jobs for local people that will encourage them to stay in the area. Sue Bowser of Croftmarsh said: “This is a milestone moment for the people of Skegness and an important step in revitalising our town and community. It is a pathway for people to carve a real future in the town, with employment, skills and learning opportunities all situated within one site, connected by an ambition to restore Skegness at the heart of East Midlands economic investment. “Having farmed the land at Croftmarsh for 30 years, it was always hoped that it could eventually be used for development. Now, it’s a chance for prospective consultants, developers and investors to look more closely at our plans and be a part of transforming Skegness’ future. It will become a new home for thousands of families, a place of ambition and prosperity, with a lasting legacy for generations to come.” As part of the proposals, the Skegness Gateway site also includes provision for a new crematorium, 78 acres of green open space, supported living options and a new local centre. The scheme has garnered wide stakeholder and public support since its launch three years ago, following a series of engagement sessions and appearances at local community events. Last November, it was described by Matt Warman, MP for Boston and Skegness as a catalyst to ‘allow people to gain the skills and knowledge they need to get the jobs they want.’ The scheme was also mentioned in the House of Commons as offering a ‘significant boon to local NHS services.’ Enabling works on the new Skegness TEC college, which is situated on the Skegness Gateway site, is already underway, following planning permission being granted in February last year. Adrian Clarke, group vice principal for corporate services at TEC Partnership, said: “The new campus will provide fantastic opportunities for the local community to undertake courses in further and higher education and develop the skills the area needs for its future.” Chris Baron, chair at Connected Coast, said: “We are seeing unprecedented investment in Skegness which is supporting the delivery of aspirational and transformational projects. “The Skegness Gateway represents a further and significant opportunity to create much-needed facilities for the area and enhance Skegness for people who live and visit here. “Together the opportunities, interventions, and investment – which includes the Towns Fund and the recently announced Long Term Plan for Towns – will bring long-term, sustainable benefits for Skegness which will be felt for generations to come.” Councillor Steve Kirk, East Lindsey District Council portfolio holder for coastal economy, said: “I am delighted to see another positive step taken towards delivering this transformational piece of investment to Skegness and East Lindsey as a whole. “By supporting these plans, we are helping to create new jobs, new education and skills development options, new homes and new opportunities for businesses and the local economy. This is yet another example that shows Skegness is a great place to live, work, play and invest. “Alongside our ongoing Towns Fund and Levelling Up projects, the positive impact of these developments will be felt for generations to come, and I look forward to continuing to see them become a reality in the months and years ahead.”

Plans to replace Nottingham office building with new apartments approved

Plans for new apartments on Nottingham’s Waterway Street, in place of a vacant 1970’s two storey office building, have been approved by the city council. The proposals for the site near Nottingham train station come from Rainier Developments, and will see the demolition of the existing Waterway House building and construction of a new build development comprising 191 apartments. The scheme is to offer 122 one bed and 69 two bed flats over a block of three to eight storeys. The development is to provide 22 car parking spaces and 4 disabled parking spaces, as well as 191 cycle parking spaces within cycle store rooms. The site on Waterway Street was purchased by Rainier Developments from Nottingham City Council last year.

Leicester City FC referred to independent Commission for alleged breach of Profitability and Sustainability Rules

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The Premier League has referred Leicester City FC to an independent Commission for an alleged breach of Profitability and Sustainability Rules (PSRs) and for failing to submit their audited financial accounts to the League. The alleged breach relates to the assessment period ending Season 2022/23, when the club was a member of the Premier League. Leicester City were relegated to the EFL Championship prior to the introduction of the Premier League’s new Standard Directions, which prescribe a timeline within which PSR cases should be heard. Therefore, the proceedings will be conducted in accordance with a timetable to be set by the independent Commission. The Club responded in a statement: “Leicester City is surprised at the actions the Premier League has taken today. The Club is extremely disappointed that the Premier League has chosen to charge LCFC now, despite the Club’s efforts to engage constructively with the Premier League in relation to the matters that are the subject of this charge, even though LCFC is not currently a Premier League club.
“LCFC remains willing and eager to engage constructively with the Premier League and the EFL to seek the proper resolution of any potential charges, by the right bodies, and at the right time. The Club continues to take careful advice about its position and, if necessary, will continue to defend itself from any unlawful acts by the football authorities, should they seek to exercise jurisdiction where they cannot do so, as occurred earlier this year. “LCFC has repeatedly demonstrated its commitment to the P&S rules through its operating model over a considerable period, achieving compliance while pursuing sporting ambitions that are entirely credible given the consistent success that the Club has achieved in that time, both domestically and in European competition. As we continue to represent the Club’s position, we will continue to fight for the right of all clubs to pursue their ambitions, particularly where these have been reasonably and fairly established through sustained sporting achievement. “The Club thanks its supporters for their understanding in this matter and for their continued support for our team, whose success on the pitch during the final weeks of the season remains our primary focus.” The news comes after Nottingham Forest was deducted four points following a breach of the Premier League’s Profitability and Sustainability Rules.

Chartered surveyors move into Northern Gateway Enterprise Centre

A multi-disciplinary firm of chartered surveyors specialising in property auctions, surveys and agency has moved to Chesterfield’s Northern Gateway Enterprise Centre. PriceLinsey boasts a combined 43 years of experience, with each team member having worn many hats in the property industry across Chesterfield, Sheffield, and also Manchester. The three directors had known one another for almost a decade before deciding to venture out on their own and join forces, with Richard and Marcus going on to meet Jodie when they worked alongside each other at another local property firm. Marcus Linsey, Director at the company, said: “Moving into the Northern Gateway Enterprise Centre was a really good move for our business. “The new grade A office accommodation with its easy-in easy-out terms suits our growing business and is superbly positioned within the heart of the town for us to connect with other solicitors and estate agents that we work alongside. The modern look and feel of the building also reflects our brand image.” The company said that with all three directors living and working in the town, it made sense to make Chesterfield PriceLinsey’s new home. Marcus continues: “Chesterfield is the perfect place to live and work being strategically located close to the M1 motorway, mainline railway station yet also within touching distance of the peak district for when you need to get away from it all! “We work closely alongside other local business including valuation work for solicitors and survey work for estate agents, and have been humbled by the positive response we have received since establishing. When we were expanding and looking for more office space, the borough council pulled out all the stops to allow us to move into the Enterprise Centre in the timescales we needed – which was short notice!” PriceLinsey is now hoping to capitalise on further growth in the town following its recent move, with Marcus adding: “We hope the business will continue to grow by increasing the number of properties sold at auction and are keen to work alongside local authorities in the region to act on their behalf. “On the other side of the business, we are carrying out an ever increasing amount of survey and valuation work. As this builds up we hope to take on an apprentice to help with this work. Who knows – we may soon need a bigger office in the NGEC!”